* Year indicates when the alignments were made.
** When selecting the HFV Arenavirus L segment, note that the aligned sequences are in the opposite orientation compared to ones available from the HFV search interface.
For filoviruses, (ebolavirus, marburgvirus, cuevavirus), three options are offered for manually-curated alignments.
From the set of all complete genome sequences, we selected one sequence per group of sequences derived from each human outbreak. Sequences from viruses passaged in non-human cells were chosen in some cases where human-derived sequences were not available. For example, from the 1967 Marburg outbreak, no sequence from a direct human source is available. For Reston viruses, there are several strains sequenced from the USA and from separate isolations in the Philippines, but only one was chosen because these viruses have not caused human outbreaks. For Lloviu virus, only one isolate, from a bat, has been sequenced to date, and no human cases are known.